Twin-S: A Digital Twin for Skull-base Surgery

Wed, 23 Nov 2022 20:50:03 +0000

Purpose: Digital twins are virtual interactive models of the real world, exhibiting identical behavior and properties. In surgical applications, computational analysis from digital twins can be used, for example, to enhance situational awareness. Methods: We present a digital twin framework for skull-base surgeries, named Twin-S, which can be integrated within various image-guided interventions seamlessly. Twin-S combines high-precision optical tracking and real-time simulation. We rely on rigorous calibration routines to ensure that the digital twin representation precisely mimics all real-world processes. Twin-S models and tracks the critical components of skull-base surgery, including the surgical tool, patient anatomy, and surgical camera. Significantly, Twin-S updates and reflects real-world drilling of the anatomical model in frame rate. Results: We extensively evaluate the accuracy of Twin-S, which achieves an average 1.39 mm error during the drilling process. We further illustrate how segmentation masks derived from the continuously updated digital twin can augment the surgical microscope view in a mixed reality setting, where bone requiring ablation is highlighted to provide surgeons additional situational awareness. Conclusion: We present Twin-S, a digital twin environment for skull-base surgery. Twin-S tracks and updates the virtual model in real-time given measurements from modern tracking technologies. Future research on complementing optical tracking with higher-precision vision-based approaches may further increase the accuracy of Twin-S.

A New Approach to Extract Fetal Electrocardiogram Using Affine Combination of Adaptive Filters

Mon, 07 Nov 2022 18:33:43 +0000

The detection of abnormal fetal heartbeats during pregnancy is important for monitoring the health conditions of the fetus. While adult ECG has made several advances in modern medicine, noninvasive fetal electrocardiography (FECG) re- mains a great challenge. In this paper, we introduce a new method based on affine combinations of adaptive filters to extract FECG signals. The affine combination of multiple filters is able to precisely fit the reference signal, and thus obtain more accurate FECGs. We proposed a method to combine the Least Mean Square (LMS) and Recursive Least Squares (RLS) filters. Our approach found that the Combined Recursive Least Squares (CRLS) filter achieves the best performance among all proposed combinations. In addition, we found that CRLS is more advantageous in extracting FECG from abdominal electrocardiograms (AECG) with a small signal-to-noise ratio (SNR). Compared with the state-of-the-art MSF-ANC method, CRLS shows improved performance. The sensitivity, accuracy and F1 score are improved by 3.58%, 2.39% and 1.36%, respectively.

Digital Health | Tony Zhang

Twin-S: A Digital Twin for Skull-base Surgery

A New Approach to Extract Fetal Electrocardiogram Using Affine Combination of Adaptive Filters